Isolating Human Monoclonal Antibodies Against Adeno-Associated Virus From Donors With Pre-existing Immunity
With the advent of single B-cell cloning technology, we can isolate antibodies against virtually any antigen to study the interaction of a given pathogen with the immune system and develop novel therapeutic strategies.Antibodies directed against the capsid of adeno-associated viruses (AAV) 15-eg1053cl are a significant obstacle to effectively lever